Dual-core city cluster is a special geographic feature during China's city cluster development. This paper uses synergy theory and growth polarity theory to establish a dual-core city cluster compound system, applies compound system synergy model and 2011-2017 panel data to measure the order of central city sub-system, order of port city sub-system and synergy of compound system of eastern China's four dual-core city clusters, providing references for theory and practice of such city cluster coordinated development. Results show their synergy displays a rising trend, entering an excellent coordinated developing stage, marked by high-low-low high. Orders of central city sub-system and coastal city sub-system are rising at same pace. Central city sub-system has experienced disorder to a rising order synergy, varying in the south and north that northern central city generally prevails the south during 2011 to 2017. Orders of port city sub-system do not show a conspicuous high-low-low-high trend, below the central city sub-system.